Structure Elucidation

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Structure Elucidation

Structure Elucidation

Advanced NMR, MS, and IR analysis to reveal complex molecular structures.
With expertise in custom synthesis, analytical services, and drug development. We are here to support all your research needs by reducing the project timeline and cost.



Impurity Identification and Quantification

We provide comprehensive impurity identification and quantification services to ensure the safety and efficacy of pharmaceutical products. Our advanced analytical techniques deliver precise and reliable results.

Chromatographic Techniques

Utilizing HPLC, UPLC, and GC to separate and quantify impurities with high precision.

Mass Spectrometry

Employing LC-MS/MS and GC-MS for accurate identification and quantification of impurities.

Spectroscopic Techniques

Using NMR and UV-Vis spectroscopy for additional structural information and quantification.

Structure Elucidation

At ARSI Canada, we specialize in structure elucidation and characterization to accelerate drug discovery and development. Using advanced techniques like mass spectrometry, NMR spectroscopy, and X-ray crystallography, our experienced team can precisely identify and confirm the chemical structures of small molecules. This allows for a detailed understanding of a compound’s biological activity, target specificity, and potential interactions with other molecules, ensuring your research is on the right track.

Our comprehensive structure elucidation services provide critical insights into the physicochemical properties of compounds, including solubility, stability, and bioavailability, which are essential for optimizing drug formulations. Whether you’re in the early stages of drug discovery or optimizing lead compounds, ARSI Canada delivers high-quality data and detailed reporting to help you move forward with confidence.

NMR Spectroscopy

Provides detailed information about the molecular structure of impurities.

Mass Spectrometry

Offers high-resolution mass data to aid in the elucidation of molecular structures.

X-Ray Crystallography

Determines the three-dimensional structure of crystalline impurities.

FTIR and Raman Spectroscopy

Used for complementary structural information and confirmation of impurity structures.

Degradation Studies

We conduct degradation studies to understand the stability of drug substances and products, identifying potential degradation products and their impact.

Stress Testing

Exposing drug substances to stress conditions (heat, light, pH, etc.) to identify degradation products.

Stability-Indicating Methods

Developing and validating methods to monitor impurities over the product’s shelf-life.

Our Process
1

Scope & Feasibility

We clarify targets, specs, safety, and timelines; align on success criteria and CDA/IP terms.

2

Route & Proposal

Route scouting, risks, and costed plan with deliverables, data package, and milestones.

3

Execution & QC

Synthesis, in-process controls, purification, and analytical verification at each stage.

4

Delivery & Support

Materials shipped per spec with full documentation and optional tech transfer support.

Who We Serve

Pharmaceuticals Biotechnology Diagnostics Agrochemicals Academia & Materials

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Quality & Compliance

We operate with rigorous QC, data integrity, and traceability aligned with international guidelines. Every shipment includes complete analytical documentation and batch records.

  • ICH-aligned practices
  • Documented methods & spectra
  • Secure IP & confidentiality
  • Clear tech transfer
Looking for recurring batches or scale-up? Ask about multi-lot programs.

Other Services

Explore our range of specialized solutions designed to support your unique needs with quality, reliability, and expertise.